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The Center of Research Excellence in Nanotechnology in collaboration with the physics department organized a joint seminar on "Multi-Scale Nanoparticles contrast agents" presented by Dr. Ahmed Obaid AlZahrani, an Associate Professor at the department of physics, King Abdul Aziz University on the 30th of March, 2016.

The event was graced by CENT personnel, faculties, and students from the physics department. The speaker started his presentation with an introduction to the topic and emphasized the importance of nanoparticles in biomedical applications in monitoring the delivery and distribution of drugs. He highlighted the desired requirements of a good imaging technique in biomedical applications to enhance effective monitoring, these requirements includes the capability of 3D imaging, large scale and subcellular resolution to allow for whole body investigation at microscopic level, other requirements are drug contrast, fast rendering time and label free to avoid contamination of the drug. He further emphasized on the different imaging techniques and their ilimitations in achieving multi-scale imaging in biomedical applications: the Confocal Microscopy and Two photon Fluorescence (TPF) microscopy has limited optical penetration in biological tissue and also requires tissue labelling which can alter the particle distribution and complicate the tissue under investigation.

He further highlighted the research proposal which is to study the use of magnetic nanoparticles as multi-scale contrast agent for both MRI and coherent anti-Stroke Raman Scattering (CARS) microscopy in a label free manner. Two magnetic nanoparticles of GD2O3 and Fe2O3 doped with rare elements were synthesized. Imaging with CARS, the full width mixing (FWM) of Gd2O3 gives strong signal and linear process while the FWM of Fe2Ogives no signal. The Fe2O3 nanoparticles gave a strong signal in the SRS detector using TPPL.The doped Gd2O3 can be image in CRS system with UCP which depends on laser power while Fe2O3 nanoparticles can be imaged in CRS using TPPL in a non-linear manner.

Some event pictures . . . 

Joint Seminar: CENT in Collaboration with the Physics Department

Joint Seminar: CENT in Collaboration with the Physics Department

Joint Seminar: CENT in Collaboration with the Physics Department