CRISPR/Cas9 Genome Editing Technology: A Revolutionizing Tool for Biological Research
Date: Wednesday, 11-MAY-2022
Time: 11:00 AM
Location: building 7, room 127
Mr. Muhammed Naeem
Master's student of Life Sciences in Department of Bioengineering (KFUPM)
Abstract: Gene editing that makes target gene modification in the genome by deletion or addition has revolutionized the era of biomedicine. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) - RNA-guided Cas9 endonuclease system has provided a fast and efficient method for precise genome editing in diverse mammalian species, including humans. The growing application of the CRISPR-Cas9 system in biomedicine and agriculture is transforming biological research by treating human genetic diseases and engineering the genome of the crops against biotic and abiotic factors. This seminar will focus on the following points.
· What is CRISPR/Cas9, how it was discovered and how does it work in the cells?
· What is the component of CRISPR/Cas9 and how CRISPR can be used to knockout (KO) and Knockin (KI) any gene?
· How CRISPR/Cas9 is transforming Biomedicine by treating genetic diseases, cancers, HIV, and Diabetes?
· How CRISPR can be used to produce high-yielding crops?
· What is the concept of Designer Babies and CRISPR Ethics?
Biography: Mr. Muhammad Naeem is a master's student of Life Sciences in Department of Bioengineering, King Fahad University of Petroleum and Minerals (KFUPM). For his MS research work, he joined Dr. Ben Lai's lab at the Institute of Biomedical Sciences Academia Sinica, Taiwan where he generated the macrophage-specific CreERT2 driver line in zebrafish by insertion of 6.5 kb insert (pRISM-CreERT2-EGFP) through CRISPR/Cas9 knock-in (KI) method. Before joining KFUPM, he completed B.S. in Genetics from the University of Agriculture Faisalabad and worked as a research assistant at the Center of Excellence in Molecular Biology (CEMB) Lahore, Pakistan.
All faculty, researchers and students are invited to attend.