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Keynote Speaker
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ETH Zurich
Prof. Richard Ernst
Laboratorium für Physikalische Chemie
HCI D 217
Wolfgang-Pauli-Str. 10
8093 Zürich
Main phone: +41 44 632 43 68
Fax: +41 44 632 12 57
E-mail:
richard.ernst@nmr.phys.chem.ethz.ch
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Education towards a Prosperous Future for All
Richard R. Ernst
Laboratorium für Physikalische Chemie, ETH Zürich
8093 Zürich, Switzerland
Our today's world is in rapid development. Many traditional
models of society are becoming soon antiquated. In such a
dynamic situation, it is no longer sufficient to memorize,
without personal reflection, dictated rules of behavior.
Survival in a modern world requires education towards
critical reflection for all members of society, irrespective
of social class and nationality. We have also to accept that
liberal education may itself induce inevitable societal
change by questioning unjustified privileges. Only by public
education for everybody, we can prevent the formation of
dangerous situations with a potentially harmful outcome.
But literacy and scientific and technological knowledge form
only part of the contents of adequate education. Equally
important is to convey also the basic ethical laws of
tolerance and compassion. Students must learn to appreciate,
in spite of all negative role models of today, that it is
not monetary personal richness that is the ultimate goal of
our endeavors, but rather richness of our spirit that may
lead to positive contributions for the sake of local and
global society, and, in the end, to personal happiness. In
this context, we might have to question certain current
developments that contradict societal fairness and
sustainability, and might unduly deprive future generations.
Curriculum vitae
Richard R. Ernst was full
Professor of Physical Chemistry since 1976.
He directed a
research group devoted to magnetic resonance spectroscopy
was director of the Laboratory of Physical Chemistry at the
ETH Zurich until 1998. He contributed to the development of
medical magnetic resonance tomo-graphy, and in collaboration
with Professor Kurt Wüthrich to the development of the NMR
structure determination of biopolymers in solution. In
addition, he was president of the Research Council of ETH
Zurich and he is presently on the editorial board of 10
scientific journals. He received numerous honours, including
the Nobel Prize for Chemistry (1991), the Wolf Prize for
Chemistry (1991), the Horwitz Prize (1991), and the Marcel
Benoist Prize (1986). He received honorary doctors degrees
of ETH Lausanne, Technische Universität Munich, Universität
Zurich, University Antwerpen, Babes-Bolyai University,
Cluj-Napoca, and University Montpellier. He is a member of
the US National Academy of Sciences, of the Royal Academy of
Sciences, London, of the Deutsche Akademie Leopoldina, of
the Russian Academy of Sciences, of the Korean Academy of
Science and Technology, and honorary member of many further
societies
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Richard R. Ernst
Born in Winterthur, Switzerland, on August 14, 1933, studied
chemistry at Eidgenössische Technische Hochschule (ETH),
Zurich. Diploma in 1962, doctor's degree in physical
chemistry (nuclear magnetic resonance spectroscopy) in 1962
After obtaining his doctorate, Ernst worked in the Physical
Chemistry Laboratory of ETH Zurich for a short time, then
spent five years in the research department of Varian
Associates at Palo Alto, California. Returning to ETH to
teach physical Chemistry in 1968, he has held a full
professorship there since 1976. He retired in 1998 from his
professorship, following the legal requirements
He was awarded the Nobel Prize in Chemistry in 1991 "for his
contribution to the development of the methodology of high
resolution nuclear magnetic resonance spectroscopy"
During the past decades, NMR spectroscopy has become one of
the most successful instrumental measuring method available
to chemistry. It is used, inter alia, to determine the
structure of molecules in solution and to gain insights into
the interactions between different kinds of molecules (such
as enzyme/substrate, soap molecule/water) and the speed of
chemical reactions. While proteins had formerly to be
crystallised before their structure could be analysed, this
can now be done by NMR spectroscopy in their natural
environment
Some first successful NMR experiments were reported as early
as 1945, but practical applications only became possible
owing to Ernst's cooperation with Weston A. Anderson in
1966, which resulted in a major increase in the sensitivity
of the method: Instead of continuously changing the
frequency of the radio waves used, the two researchers
exposed their samples to short intensive radio-frequency
oscillations, measured the signal as a function of the
oscillation time, repeated the measurements at short
intervals, added the signals up in a computer and
transferred them by means of a mathematical operation
(Fourier transformation) into an NRM spectrum for
evaluation. In so doing, they laid the foundations for
modern nuclear magnetic resonance spectroscopy. Further work
added two-, three- and multi-dimensional variants of NMR
spectroscopy which made it possible to obtain a more highly
differentiated picture larger proteins owing to the use of
several oscillation sequences (rather than individual
radiofrequency oscillations) and several time variables. In
this way, it was possible to determine the three-dimensional
structure of organic and inorganic compounds, proteins and
other biological macromolecules in solution at a level of
accuracy comparable to the results of X-ray crystallography
in crystalline preparations
The recent, highly successful applications of NMR to medical
imaging, in the form of MRI (Magnetic Resonance Imaging),
are also taking advantage of the principles that have been
contributed by Ernst and his co-workers
After his retirement, he concentrated more on his interests
in improving the relation between science and society. He is
advocating a more active role of academics and scientists in
shaping our global future. In addition, he developed a
fascination for the beauty and depth of Tibetan painting art
and for the profound Tibetan Buddhist philosophy
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