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Development of convenient palladium-catalyzed synthetic methodologies for heterocyclic compounds
Date: Wednesday, October 19th 2016 
Time: 11:00 AM 
Location: Building 4, Room 125


Dr. Muhammad Sharif
King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, KSA

Hetroatom containing compounds constitute an important class of biologically active compounds. Thus, the development of new syntheses and improved methods for their preparation continues to be a challenging and active area of research. Quinazolinones represent an important class of nitrogen heterocycles with various biological activities. Among all the substituted quinazolinones, 4(3H)-quinazolinones are more valuable with numerous biological activities that have been reported, while the methodologies for these compounds syntheses are still rare.
On the other hand, Amides are also important class of building blocks in modern organic synthesis, with broad applications in advanced materials, pharmaceuticals, and building blocks for fine chemicals. Traditionally, amides were produced by the reaction of carboxylic acids with the corresponding amines. In recent years, several other procedures were developed as well, such as aminocarbonylation of organo halides, oxidative amidation of aldehydes and alcohols, oxidation of amines, rearrangements and so on.
All faculty, researchers and graduate students are invited to attend.
There will be a get-together with refreshments at 10:45-11:00 a.m.

Chemistry Department, College of Sciences
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