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You are cordially invited to attend this week's CSE 699/ICS 599/COE 599 following Graduate Seminars:

Location: 22 - 130

Date: Wednesday Nov. 20, 2013 

First Seminar:

Duration: 2:30 - 3:10 pm

Speaker: Mr. Naef Dael, ICS Department 

Title: Detecting protein complexes in a PPI network: a gene ontology based multi-objective evolutionary approach

Abstract

Protein complexes play an important role in cellular mechanism. Identification of protein complexes in protein–protein interaction (PPI) networks is the first step in understanding the organization and dynamics of cell function. Several high-throughput experimental techniques produce a large amount of protein interactions, which can be used to predict protein complexes in a PPI network. We have developed an algorithm PROCOMOSS (Protein Complex Detection using Multi-objective Evolutionary Approach based on Semantic Similarity) for partitioning the whole PPI network into clusters, which serve as predicted protein complexes. We consider both graphical properties of a PPI network as well as biological properties based on GO semantic similarity measure as objective functions. Here three different semantic similarity measures are used for grouping functionally similar proteins in the same clusters. We have applied the PROCOMOSS algorithm on two different datasets of Saccharomyces cerevisiae to find and predict protein complexes. A real-life application of the PROCOMOSS is also shown here by applying it in the human PPI network consisting of differentially expressed genes affected by gastric cancer. Gene ontology and pathway based analyses are also performed to investigate the biological importance of the extracted gene modules.

Second Seminar:

Duration 3:10 - 3:50 pm

Speaker: Mr. Farrukh Shahzad, ICS Department

Title: Secure Overlay Cloud Storage with Access Control and Assured Deletion

Abstract

Cloud storage services allow us to outsource data backups off-site to a third-party, which will reduce data management costs. However, there must be some security guarantees for the outsourced data, which is now maintained by third parties. The authors of this paper design and implement FADE, a secure overlay cloud storage system that achieves fine-grained, policy-based access control and file assured deletion. It associates outsourced files with file access policies, and assuredly deletes files to make them unrecoverable to anyone upon revocations of file access policies. To achieve such security goals, FADE is built upon a set of cryptographic key operations that are self-maintained by a quorum of key managers that are independent of third-party clouds. In particular, FADE acts as an overlay system that works seamlessly atop today’s cloud storage services. They implement a proof-of-concept prototype of FADE atop Amazon S3, one of today’s cloud storage services and  conduct extensive empirical studies, and demonstrate that FADE provides security protection for outsourced data, while introducing only minimal performance and monetary cost overhead. This work provides insights of how to incorporate value-added security features into today’s cloud storage services.

Biography

Mr. Farrukh Shahzad was born in Karachi, Pakistan. He did his BE(Electrical Eng..) from the NED University of Engineering & Technology, Karachi, Pakistan in 1992 and his MSEE from King Fahd University of Petroleum & Minerals (KFUPM), Dhahran, Saudi Arabia in 1996. He is currently a PhD student and lecturer at KFUPM. In 1996, he moved to USA. He has 16 years field experience in product design, software development, engineering, and implementation of many M2M and satellite based remote monitoring systems. His current interests include wireless sensor networks, Cloud storage security, Big Data analytics, Data sciences, Machine learning and business intelligence. He is US copyright holder of four Engineering soft wares. His research activities resulted in publication of more than 10 technical papers in IEEE and other journals and conferences.